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These results, together with a past report exhibiting that a little-molecule ACKR3 agonist CCX771 reveals anxiolytic-like actions in mice,2 support the notion of focusing on ACKR3 as a novel approach to modulate the opioid program, which could open up new therapeutic avenues for opioid-relevant

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These outcomes, together with a prior report displaying that a small-molecule ACKR3 agonist CCX771 exhibits anxiolytic-like behavior in mice,2 help the strategy of targeting ACKR3 as a singular technique to modulate the opioid system, which could open up new therapeutic avenues for opioid-connec